Frontiers in Polymer and Biomolecular Chemistry

 Dates:     March 2-4, 2015

 Location:  Tel Aviv University Campus,
            Melamed Hall, Shenker building,
            Raymod and Beverly Faculty of Exact Sciences


 Organizers: Tamar Schlick: schlick@nyu.edu (054-996-7471)
             Gil Markovich: gilmar@post.tau.ac.il (050-849-0225)

Program

 



  ~~~~~~   Monday, March 2   ~~~~~~

  9:30 - 10:00    Gathering and Refreshments

  10:00 - 10:15  Welcome: Yoav Henis, TAU Vice President for Research & Development, and Ra'anan Rein, TAU Vice President

  Special Guest Lecture

  10:20 -10:45  Charles Cantor,  Retrotope. Site Specifically Deuterated Polyunsaturated Fatty Acids: A New Approach to Treat Diseases Caused or Exacerbated by Oxidative Stress
  10:45 -10:50  Discussion


  Session I:  Nanoconstructs (Talks 1-3)
  Chair: Gil Markovich and Tamar Schlick


 10:50 - 11:15  Ned Seeman, NYU.  DNA:  Not Merely the Secret of Life
 11:15 - 11:20  Discussion

 11:20 - 11:40  Coffee Break

 11:40 - 12:05  Roey  Amir, TAU. Smart polymeric amphiphiles
 12:05 - 12:10  Discussion

 12:10 - 12:35  Yuval Ebenstein, TAU. Tricking Enzymes to Highlight Genomic Information
 12:35 - 12:40  Discussion

 12:40 - 12:50  Open Discussion (meeting goals, etc.)

 Lunch

   Session II:   Bio-organic and Medicinal Chemistry (Talks 4-6)
   Chair: Michael Gozin, TAU


 14:30 - 14:55   Daniella Buccella, NYU. Fluorescent Probes for Biologically Relevant Metal Ions: Shedding Light on Magnesium Homeostasis
 14:55 - 15:00   Discussion

 15:00 - 15:25   Micha Fridman, TAU. Membranes as Drug Targets
 15:25 - 15:30   Discussion

 15:30 - 15:50   Coffee Break

 15:50 - 16:15   Bobby Arora, NYU. Protein Domain Mimics as Modulators of Protein-Protein Interactions

 16:15 - 16:20   Discussion

   Session III: Biophysics and Biopolymer Experimentation
   Chair:  Yael Roichman, TAU



 16:20 - 16:45   Roy Beck-Barkai, TAU. Order and Disorder in Biomacromolecular Complexes
 16:45 - 16:50   Discussion

 16:50 - 17:15   Kent Kirshenbaum, NYU. Crafting Sequence-Structure-Function Relationships for Biomimetic Polymers
 17:15 - 17:20   Discussion

 Evening on your own to relax and enjoy beautiful Tel Aviv



 ~~~~~~ Tuesday, March 3 ~~~~~~


 Session IV: Computation and Design (Talks 9-12)
 Chair:  Oded Hod, TAU Oded Hod, TAU


 10:00 - 10:25 Tamar Schlick, NYU and TAU GRI:  Multiscale modeling of the chromatin fiber

 10:25 - 10:30 Discussion

 10:30 - 10:55 Doron Shabat, TAU. Quinone-Methide Species - A Gateway to Functional Molecular Systems

 10:55 - 11:00 Discussion

 11:00 - 11:20 Coffee Break

 11:20 - 11:45 John Zhang, NYU and NYU-Shanghai: Structure, Dynamics and Function of Proteins from Computer Simulation
 11:45 - 11:50 Discussion

 11:50 - 12:15 Nir Ben Tal, TAU. Energetic and Structural Determinants of Ion Selectivity in Human Copper Transporter 1
 12:15 - 12:20 Discussion

 Return to hotel, departure for excursion to Caesaria (around 14:00), followed
 by dinner at a seaside restaurant

 ~~~~~~ Wednesday, March 4 ~~~~~~


 Session V: NMR and Applications (Talks 13-16)
 Chair:


 10:00 - 10:25  Alexej Jerschow, NYU. MRI of Batteries
 10:25 - 10:30  Discussion

 10:30 - 10:55 Amir Goldbourt, TAU. The atomic resolution model of M13 bacteriophage virus, derived from magic-angle spinning NMR and Rosetta modeling, reveals a quadrupled hydrophobic binding epitope in its capsid

 10:55 - 11:00 Discussion

 11:00 - 11:30 Coffee Break

 11:30 - 11:55 Nate Traaseth, NYU. Probing the Ion-Coupled Transport Mechanism of Multidrug Efflux Pumps Using NMR Spectroscopy
 11:55 - 12:00 Discussion

 12:00 - 12:25 Gil Navon, TAU. Molecular Imaging of Tumors Using Chemical Exchange Saturation Transfer MRI
 12:25 - 12:30 Discussion

 12:30 - 13:00  Concluding discussion
 Adjourn