DiSCO 1.2 Manual

1. System Requirements
2. Installation
3. Running Instructions
4. Program Files
5. Input Files and Parameters
6. Output Files

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1. SYSTEM REQUIREMENTS

SGI IRIX IP22 or higher (type "hinv" to check)    [Back to Top]

2. INSTALLATION

    tar -xvf DiSCO-1.2.tar  
(A new directory DiSCO-1.2 will be produced.)

--- If you already have QNIFFT:
Copy the executable file qnifft to the directory DiSCO-1.2

--- If you do not have QNIFFT:
Download from Pyle Lab.

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3. RUNNING INSTRUCTION

Copy your standard PDB file (not edited) to the directory DiSCO-1.2;
in the directory DiSCO-1.2, type
    DiSCO

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4. PROGRAM FILES

5. INPUT FILES AND PARAMETERS

macromolecule's PDB file
1. absolute temperature T [K]
2. monovalent salt concentration Cs [M]
3. minimization distance d [Angstrom]
4. amount of models (with different N)
5. maximal / minimal number of discrete surface charges N
6. output directory   
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6. OUTPUT FILES