Molecular Modeling Course 99
Tamar Schlick

Tamar Schlick

New York University and Howard Hughes Medical Institute

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Updated Page: Professor Schlick

Chemistry Department and Courant Institute of Mathematical Sciences,
251 Mercer Street, New York, NY 10012 USA
Telephone: (212) 998-3116 -3596 (sec.), Fax: (212) 995-4152, E-mail:

Tamar Schlick received her B.S. degree in Mathematics from Wayne State University in 1982 and her M.S. (1985) and Ph.D. (1987) degrees in Applied Mathematics from the Courant Institute of Mathematical Sciences, New York University. Following a two-year NSF Postdoctoral Fellowship at NYU and the Weizmann Institute, she joined the faculty of Chemistry and Mathematics at NYU, where she is Professor. Since 1994 she has also been an Associate Investigator of the Howard Hughes Medical Institute and a member of the Biochemistry Department, NYU Medical Center, and since 1995 a member of the Computer Science Department, Courant Institute.

Areas of Technical Specialization

Mathematical Biophysics/Computational Chemistry: algorithm development for biomolecular simulations (energy minimization and molecular dynamics) and applications to DNA supercoiling and protein dynamics. Numerical Analysis and Scientific Computing: nonlinear unconstrained optimization, truncated Newton methods, stiff differential equations, conjugate gradient methods with application-tailored preconditioners, modified Cholesky factorizations, sparse linear systems, and multiscale methods.

Honors and Awards
  • Keynote Lecture: Consilience in the Biomolecular Sciences, Burroughs Wellcome Fund workshop, ``Doing Science at the Interface'', Berkeley, 1998
  •  VCH Annual Lecture, Indiana University/Purdue University, Indianapolis, 1996
  •  Howard Hughes Medical Institute Associate Investigator, 1994-2003
  •  Alfred P. Sloan Research Fellow, 1993-1995
  •  NYU Distinguished Recent Alumna, 1993
  •  NSF Presidential Young Investigator, 1991-1996
  •  1991 Searle Scholar, 1991-1994
  •  Whitehead Presidential Fellow, NYU, 1991
  •  Marie Curie American Fellow, AAUW Educational Foundation, 1990-1991
  •  K.O. Friedrichs Prize for Outstanding Dissertation in Mathematics, Courant Institute, 1988
  •  J. Krakauer Prize for Outstanding Dissertation in the Sciences, NYU, 1988
  •  NSF Postdoctoral Fellow in the Mathematical Sciences, 1987-1989
  •  Weizmann Postdoctoral Fellow, 1988
  •  Dean's Dissertation Fellow, NYU, 1986-1987
  •  Wayne State University Merit Scholar, 1978-1982
  •  Phi Beta Kappa, National Honor Society, Graduation with Excellence in Mathematics and French, and Outstanding Leadership Award in University Programs, Wayne State University, 1982
Community Service and Professional Activities
  • Member, AAAS, ACS, AMS, AWM, Biophysical Society, SIAM, and SMB
  •  Associate Editor: Journal of Computational Physics, 1997- ; Springer-Verlag Lecture Notes in Computational Science and Engineering, 1996- ; J. Theoretical Biology, 1995-
  •  Co-Organizer (with W. Olson, B. Coleman, and I. Tobias), DIMACS/PMMB Workshop on DNA Topology, Rutgers University, 1997
  •  Member, NSF Academic Research Infrastructure Program Review Panel, 1996
  •  Editor, NYU Electronic Journal of Sciences and Arts, 1995 -
  •  Member, Advisory Board, The Burroughs-Wellcome Fund for Interdisciplinary Programs Between the Physical and Biological Sciences, 1995 -
  •  Co-Organizer (with A. Brandt), Workshop on Multigrid Techniques With Applications to Molecular Dynamics, Weizmann Institute, 1995
  •  Organizer, Molecular Dynamics minisymposium, SIAM Annual Meeting, 1995
  •  Scientific Counselor, NIH National Center for Biological Information, Chair: David J. Lipman, 1994-1999
  •  SIAM representative, AMS-ASA-AWM-IMS-MAA-NCTM-SIAM Committee on Women in the Mathematical Sciences, 1994-1997
  •  Member, National Research Council Panel, Report on Mathematical Challenges in Computational Chemistry, Chair: F. Stillinger, 1994-1995
  •  Chair, Research Advisory Board, NIH Parallel Resource for Structural Biology, University of San Diego/SDSC/Scripps, 1994-1998
  •  Board Member, New Series in Scientific Computing, Oxford University Press, Series Editor: D.G. Truhlar, 1993 -
  •  Member, NSF New Technologies Postdoctoral Program Review Panel, 1991-1995
  •  Organizer and Faculty Lecturer, Molecular Structures & Dynamics Workshop, Mathematical Sciences Research Institute, UC Berkeley, 1992
Ten Selected Publications
  1. E. Barth and T. Schlick, Overcoming stability limitations in biomolecular dynamics: I. Combining force splitting via extrapolation with Langevin dynamics in LN, J. Chem. Phys. 109: 1617-1632 (1998).
  2.  P. Derreumaux and T. Schlick, The loop opening/closing motion of the enzyme triosephosphate isomerase, Biophys. J. 74: 72-81, 1998.
  3.  T. Schlick, M. Mandziuk, R.D. Skeel, and K. Srinivas, Nonlinear resonance artifacts in molecular dynamics simulations, J. Comp. Phys. 139: 1-29, 1998.
  4.  T. Schlick, E. Barth, and M. Mandziuk, Biomolecular dynamics at long timesteps: Bridging the timescale gap between simulation and experimentation, Ann. Rev. Biophys. Biomol. Struc. 26:179-220, 1997.
  5.  R.D. Skeel, G. Zhang, and T. Schlick, A family of symplectic integrators: Stability, accuracy, and molecular dynamics applications, SIAM J. Sci. Comp., 18:202-222, 1997.
  6.  H. Jian, A. Vologodskii, and T. Schlick, A combined wormlike-chain and bead model for dynamic simulations of long DNA, J. Comp. Phys. 136, 168-179, 1997.
  7.  T. Schlick, Modeling superhelical DNA: Recent analytical and dynamic approaches, Curr. Opin. Struc. Bio., 5:245-262, 1995. (Special issue on Theory and Simulation, edited by B. Honig).
  8.  G. Ramachandran and T. Schlick, Solvent effects on supercoiled DNA explored by Langevin dynamics simulations, Phys. Rev. E, 51:6188-6203, 1995.
  9.  T. Schlick and W. K. Olson, Supercoiled DNA energetics and dynamics by computer simulation, J. Mol. Biol., 223:1089-1119, 1992.
  10.  T. Schlick and W.K. Olson, Trefoil knotting revealed by molecular dynamics of supercoiled DNA, Science, 257:1110-1115, 1992.

For further information, contact T. Schlick by email ( phone (998-3116) or fax (995-4152).