Movies of Supercoiled DNA Dynamics
Movies give us more vivid views of how supercoiled DNA moves in solvent and how
other factors (e.g., the DNA supercoiling, the salt concentration) affect the process.
Both salt and supercoiling have very strong effects on DNA kinetics.
- High Salt, High Supercoiling
At high salt, the slithering mechanism -- the bidirectional tracking along
the superhelix -- dominates in supercoiled DNA dynamics, which can be
clearly observed in this movie. The movie also displays the event of a
branch formation. (3 kb, 0.2 M, sigma=-0.06, 0.6 ms simulation)
- Low Salt, Low Supercoiling
At low salt and/or low supercoiling, DNA conformations undergo rapidly global changes and site juxtaposition events become less correlated, as shown in the following movies. (3 kb, 0.01 M, sigma=-0.02, 0.6 ms simulation).
To view the videos, you must have quicktime video player:
Page and Movies Created by Jing Huang.
For questions, comments, etc., please write to email@example.com
Last modified Sept 18, 2000.